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Deep TMS™ Reaches Deeper, Broader Areas of the Brain to Effectively Treat Depression. Learn About a New Rx Treatment Option for MDD in Adults. Learn About a New Rx Treatment Option for MDD in Adults. Despite the scarcity of high-quality evidence, fluoxetine (alone or in combination with CBT) seems to be the best choice for the acute treatment of moderate-to-severe depressive disorder in children and adolescents. Deep TMS™ is Effective in Treating Depression. Learn About an MDD Prescription Medicine That Is Approved as an Add-On Treatment Option.. 1177/0018578720925384 One study in which fluoxetine or citalopram (Celexa) was augmented with buspirone (Buspar), 10 to 30 mg twice daily, showed no improvement in depression scores or response rates compared with. This Add-On May Help Adults Decrease Depression Symptoms More Than Just An Antidepressant. Learn How This New Treatment Can Help Manage Symptoms of MDD. The presence of TRD contributes to the morbidity and excess mortality associated with MDD and has been linked to significantly increased health care expenses. There was not enough evidence, however, for the panel to determine the comparative effectiveness of psychotherapy versus fluoxetine Major depressive disorder (MDD) affects at least 5% of the population, with a lifetime prevalence estimated at 14%.

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